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STOCK Nptxrtm1.1Sud/J
Cat. No.: CEMM-07251009
Common Name: Npr cKO
Exon 2 of the mouse Nptxr (neuronal pentraxin receptor) gene is flanked by loxP sites in this Npr cKO strain. Cre recombinase-mediated excision of the floxed region creates a frameshift and functional knock-out in which exon 1 encodes only a small N-terminal stub.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Nptxrtm1.1Sud
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Nptxr
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| Gene Name |
neuronal pentraxin receptor
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| Chromosome |
15
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| MGI Accession ID | show more close |
| Strain of Origin |
(C57BL/6J x 129S6/SvEvTac)F1
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| Molecular Note |
A loxP site was introduced to intron 1, and a loxP-FRT Neo-FRT F3 cassette was placed in intron 2 via homologous recombination. Flp-mediated recombination removed the FRT flanked neo cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
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| Breeding Considerations |
Heterozygous and homozygous floxed mice are viable and fertile.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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