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STOCK Sp8tm2Smb/J
Cat. No.: CEMM-07250498
These floxed mutant mice possess loxP sites flanking the Sp8 coding region. They may be useful in applications related to the study of olfactory neurogenesis, and limb and craniofacial development.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Sp8tm2Smb
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| Allele Name |
targeted mutation 2
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Sp8
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| Gene Name |
trans-acting transcription factor 8
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| Chromosome |
12
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
An FRT flanked neomycin selection cassette and a 5' loxP site were inserted in intron 2. A second loxP site was placed downstream of the zinc finger domain and stop codon in the 3' UTR. The coding sequence of the gene was thus surrounded by loxP sites. Sp8tm1Smb was derived from this allele.
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| HUSBANDRY | |
|---|---|
| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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