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STOCK Nlgn3tm2Sud/J
Cat. No.: CEMM-07250299
This Nlgn3 (neuroligin 3) strain carries a hypomorphic mutation that reduces expression to approximately 10% that of wildtype levels in brain tissue.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Nlgn3tm2Sud
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| Allele Name |
targeted mutation 2
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| Allele Attributes |
Conditional ready (e.g. floxed); Reporter; Hypomorph
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| Gene Symbol |
Nlgn3
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| Gene Name |
neuroligin 3
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| Chromosome |
X
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| Expressed Genes |
FLAG, FLAG octapeptide,
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
The signal sequence coding region of exon 2 was replaced by preprotrypsin signal sequence followed by triplicated FLAG epitope coding sequence. Exons 2 and 3 were flanked by loxP sites and an FRT flanked neomycin resistance cassette was placed in intron 2. Flp-mediated recombination removed the neo cassette. This allele is hypomorphic.
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For Research Use Only.
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