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B6.129P2-Pvalbtm1(cre)Arbr/J
Cat. No.: CEMM-07250334
Common Name: B6 PVcre
PV-Cre knock-in mice express Cre recombinase in parvalbumin-expressing neurons (such as interneurons in the brain and proprioceptive afferent sensory neurons in the dorsal root ganglia), without disrupting endogenous Pvalb expression. These mice may be useful in studying neuronal development, differentiation, and physiology.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Pvalbtm1(cre)Arbr
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Pvalb
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| Gene Name |
parvalbumin
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| Chromosome |
15
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Most neurons that express parvalbumin including interneurons in the brain and proprioceptive afferent sensory neurons in the dorsal root ganglia
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| Strain of Origin |
129P2/OlaHsd
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| Molecular Note |
An IRES-Cre-pA cassette was inserted into the 3' UTR of exon 5.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes. See Detailed Description for information on germline Cre expression.
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For Research Use Only.
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