Online Inquiry
C57BL/6N-Tg(Calcrl, cre)4688Nkza/J
Cat. No.: CEMM-07250488
These mice express Cre recombinase under the control of the murine calcitonin receptor-like (Calcrl) promoter. This strain represents an effective tool for generating mossy cell specific-targeted mutants.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Calcrl,cre)4688Nkza
show more
close
|
| Allele Name |
transgene insertion 4688
show more
close
|
| Allele Attributes |
Recombinase-expressing
show more
close
|
| Gene Symbol |
Tg(Calcrl,cre)4688Nkza
show more
close
|
| Gene Name |
transgene insertion 4688
show more
close
|
| Chromosome |
UN
show more
close
|
| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
show more
close
|
| MGI Accession ID | show more close |
| Site of Expression |
Cre recombinase expression is seen in mossy cells of the hilar region of the hippocampus.
show more
close
|
| Strain of Origin |
C57BL/6NTac
show more
close
|
| Molecular Note |
A 50.9 kb BAC containing the 5'-transcriptional regulatory region of the murine calcitonin receptor-like (Calcrl) gene was coinjected with a nuclear localization signal (nls)-Cre cDNA with an HSP70 minimal promoter, into fertilized C57BL/6NTac oocytes. A line was established from mice of founder line 4688, with insertion of the transgene and Cre cDNA occurring at a single locus.
show more
close
|
| HUSBANDRY | |
|---|---|
| Breeding Considerations |
When maintaining a live colony, hemizygous mice may be bred together.
show more
close
|
For Research Use Only.
Related Products