STOCK Ngfrtm1.1Vk/BnapJ

Cat. No.: CEMM-07250849

Common Name: p75NTR-FX flox
These p75NTR-FX, mutant mice possess loxP sites flanking exons 4 through 6 of the Ngfr gene. This strain may be useful for generating conditional mutations in applications related to neuronal electrophysiology, neuronal progenitor cell cycle and neural cell survival.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Ngfrtm1.1Vk
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Allele Name
targeted mutation 1.1
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Allele Attributes
Conditional ready (e.g. floxed); No functional change
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Gene Symbol
Ngfr
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Gene Name
nerve growth factor receptor (TNFR superfamily
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Chromosome
11
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MGI Accession ID show more close
Strain of Origin
129S2/SvPas
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Molecular Note
A loxP site was inserted upstream of exon 4. A floxed neo cassette was inserted downstream of exon 6. Cre-mediated recombination removed the neo cassette and exons 4 through 6 remained floxed.
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HUSBANDRY
Breeding Considerations
When maintaining a live colony, these mice can be bred as homozygotes.
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Breeding Strategy
Homozygote x Homozygote
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For Research Use Only.
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