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STOCK Ngfrtm1.1Vk/BnapJ
Cat. No.: CEMM-07250849
Common Name: p75NTR-FX flox
These p75NTR-FX, mutant mice possess loxP sites flanking exons 4 through 6 of the Ngfr gene. This strain may be useful for generating conditional mutations in applications related to neuronal electrophysiology, neuronal progenitor cell cycle and neural cell survival.
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Status | Live Mouse Frozen Embryo |
Age | 4 weeks 12 weeks Customized Age |
Sex | Male Female |
GENETICS | |
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Allele Symbol |
Ngfrtm1.1Vk
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Allele Name |
targeted mutation 1.1
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Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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Gene Symbol |
Ngfr
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Gene Name |
nerve growth factor receptor (TNFR superfamily
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Chromosome |
11
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MGI Accession ID | show more close |
Strain of Origin |
129S2/SvPas
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Molecular Note |
A loxP site was inserted upstream of exon 4. A floxed neo cassette was inserted downstream of exon 6. Cre-mediated recombination removed the neo cassette and exons 4 through 6 remained floxed.
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HUSBANDRY | |
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Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
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Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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