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STOCK Mir325tm1Mtm/Mmjax
Cat. No.: CEMM-07250455
These microRNA 325 conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. lacZ expression is observed in the central nervous system, brain, spinal cord and visual sensory system.. This mutant mouse strain may be useful in studies of microRNA biology.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Mir325tm1Mtm
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); Reporter; Null/Knockout
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| Gene Symbol |
Mir325
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| Gene Name |
microRNA 325
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| Chromosome |
X
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| Expressed Genes |
lacZ, beta-galactosidase, E. coli
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| MGI Accession ID | show more close |
| Site of Expression |
Central nervous system at E11.5; visual sensory system, spinal chord, and broad brain expression at E18.5.
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| Strain of Origin |
129P2/OlaHsd
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| Molecular Note |
A targeting vector was designed to insert an FRT site followed by a lacZ gene, a loxP site, a neomycin cassette, an FRT site and a loxP site (FRT lacZ-loxP-Neo-FRT loxP) upstream of the microRNA stem loop and one loxP site immediately downstream of the microRNA stem loop.
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For Research Use Only.
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