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B6.Cg-Slc6a13tm1.1Ncd/J
Cat. No.: CEMM-07250768
Common Name: GAT2-flox
GAT2-flox mice possess loxP sites flanking exons 5-7 of the neurotransmitter transporter, GABA gene. This strain may be useful for studying the role of GABA neurotransmitter and taurine levels in the brain.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Slc6a13tm1.1Ncd
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Slc6a13
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| Gene Name |
solute carrier family 6 (neurotransmitter transporter
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| Chromosome |
6
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| MGI Accession ID | show more close |
| Strain of Origin |
(129S6/SvEvTac x C57BL/6J)F1
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| Molecular Note |
A loxP site was inserted upstream of exon 5. An FRT flanked neo cassette with a 3' loxP site was inserted downstream of exon 7. Flp-mediated recombination removed the neo cassette and left exons 5 through 7 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, mice homozygous for the floxed allele may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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