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STOCK Gt(ROSA)26Sortm1(CAG-Dmrt1, -EGFP)Zark/J
Cat. No.: CEMM-07251033
Common Name: CAG-STOP-Dmrt1-Gfp
CAG-Stop-Dmrt1-Gfp knock-in mice conditionally express Dmrt1 (doublesex and mab-3 related transcription factor 1) and an EGFP reporter. This strain may be useful for studying vertebrate sex determination.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Gt(ROSA)26Sortm1(CAG-Dmrt1,-EGFP)Zark
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); Reporter; Inserted expressed sequence
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| Gene Symbol |
Gt(ROSA)26Sor
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| Gene Name |
gene trap ROSA 26
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| Chromosome |
6
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| MGI Accession ID | show more close |
| Site of Expression |
The CAG promoter allows a widespread pattern of expression.
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| Strain of Origin |
129S1/Sv-Oca2+ Tyr+ Kitl+
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| Molecular Note |
The targeting vector contains a CAG promoter followed by a loxP-STOP-loxP (containing a Pgk-Neo in reverse orientation), human beta-globin (HBB) 5'; UTR, mouse Dmrt1 coding sequence, an FRT flanked IRES-EGFP and a triple polyA inserted downstream of exon of the ROSA26 locus.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF2/J
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| Breeding Considerations |
When maintaining a live colony, these mice are bred by homozygote sibling matings.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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