Online Inquiry
B6;129S4-Cux1tm1(cre/ERT2)Zjh/J
Cat. No.: CEMM-07251052
Common Name: Cux1-2A-CreER
Cux1-2A-CreER knock-in mice express tamoxifen-inducible CreERT2 fusion protein from the mouse Cux1 (cut-like homeobox 1) promoter in CUX1-positive cortical glutamatergic pyramidal neurons (PyNs).
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Cux1tm1(cre/ERT2)Zjh
show more
close
|
| Allele Name |
targeted mutation 1
show more
close
|
| Allele Attributes |
Recombinase-expressing; Inducible
show more
close
|
| Gene Symbol |
Cux1
show more
close
|
| Gene Name |
cut-like homeobox 1
show more
close
|
| Chromosome |
5
show more
close
|
| MGI Accession ID | show more close |
| Strain of Origin |
(C57BL/6 x 129S4/SvJae)F1
show more
close
|
| Molecular Note |
The allele was generated by inserting a 2A-CreER expression cassette in-frame before the STOP codon of the Cux1 gene. The targeting vectors generated using BAC clones from the RPCI-23&24 library were electroporated into a 129SVj/B6 hybrid ES cell line (v6.5). The Resulting ES cell clones were used for tetraploid complementation to obtain male heterozygous mice.
show more
close
|
| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF2/J
show more
close
|
| Breeding Considerations |
Heterozygotes and homozygotes are viable and fertile.
show more
close
|
| Breeding Strategy |
Heterozygote x Heterozygote
show more
close
|
For Research Use Only.
Related Products