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STOCK Gfra1tm1.1Wql/J
Cat. No.: CEMM-07250818
Common Name: Gfra1 flox
Gfra1 flox mice possess loxP sites flanking exon 6 glial cell line derived neurotrophic factor family receptor alpha 1 (Gfra1) gene making them useful for tissue specific GFRA1 deletion. These floxed mice are useful when studying RET signaling during development.
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Status | Live Mouse Frozen Embryo |
Age | 4 weeks 12 weeks Customized Age |
Sex | Male Female |
GENETICS | |
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Allele Symbol |
Gfra1tm1.1Wql
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Allele Name |
targeted mutation 1.1
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Allele Attributes |
Conditional ready (e.g. floxed)
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Gene Symbol |
Gfra1
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Gene Name |
glial cell line derived neurotrophic factor family receptor alpha 1
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Chromosome |
19
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MGI Accession ID | show more close |
Strain of Origin |
129
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Molecular Note |
A loxP site was inserted upstream of exon 6 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 6 via homologous recombination. Flp mediated recombination removed the neo cassette.
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HUSBANDRY | |
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Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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