STOCK Gfra1tm1.1Wql/J

Cat. No.: CEMM-07250818

Common Name: Gfra1 flox
Gfra1 flox mice possess loxP sites flanking exon 6 glial cell line derived neurotrophic factor family receptor alpha 1 (Gfra1) gene making them useful for tissue specific GFRA1 deletion. These floxed mice are useful when studying RET signaling during development.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Gfra1tm1.1Wql
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Allele Name
targeted mutation 1.1
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Allele Attributes
Conditional ready (e.g. floxed)
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Gene Symbol
Gfra1
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Gene Name
glial cell line derived neurotrophic factor family receptor alpha 1
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Chromosome
19
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MGI Accession ID show more close
Strain of Origin
129
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Molecular Note
A loxP site was inserted upstream of exon 6 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 6 via homologous recombination. Flp mediated recombination removed the neo cassette.
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HUSBANDRY
Breeding Considerations
When maintaining a live colony, homozygous mice may be bred together.
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Breeding Strategy
Homozygote x Homozygote
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For Research Use Only.
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