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B6.129(SJL)-Scn4btm1.1Geh/RahJ
Cat. No.: CEMM-07250638
Common Name: Scn4b floxed
Scn4b floxed mice may be useful for studying the role of sodium channel beta subunits on the gating properties of sodium channels.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Scn4btm1.1Geh
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Scn4b
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| Gene Name |
sodium channel
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| Chromosome |
9
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
A targeting vector was designed to insert a loxP site, followed by a FRT flanked neomycin resistance (neo) cassette, upstream of exon 2, and a second loxP site downstream of exon 2. Flp-mediated recombination removed the FRT flanked neo cassette leaving exon 2 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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