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STOCK Fzd3tm2.1Nat/J
Cat. No.: CEMM-07250516
The largest coding exon of the Fzd3 (frizzled homolog 3 (Drosophila)) gene is flanked by loxP sites and tagged by hemagglutinin in this conditional mutant strain.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Fzd3tm2.1Nat
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| Allele Name |
targeted mutation 2.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Fzd3
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| Gene Name |
frizzled class receptor 3
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| Chromosome |
14
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
The following elements were inserted into the mouse Fzd3 (frizzled homolog 3 (Drosophila)) locus via homologous recombination: a loxP site in intron 2, a 3HA (hemagglutinin) epitope in the coding region between the cysteine-rich domain and the first transmembrane domain, a loxP site in intron 3, and an Frt-flanked PGK-neo cassette. The neomycin cassette was removed by germline Flp-mediated recombination.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF2/J
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| Breeding Considerations |
Homozygous and heterozygous floxed mice are viable and fertile.
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For Research Use Only.
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