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Mouse Models
Site-specific recombinase (SSR) system is widely used in genetically modification, especially the generation for conditional KO and inducible KO mouse models. For making it more efficient and easier, mouse models with special functions have been generated, such as tissue-specifically expressing Cre, inducible expressing Cre, Split-Cre, floxed (target gene were flanked by loxP sites) mouse, et al.
For assisting our global customers making better breakthrough in their research areas, Creative Biogene offers various of mouse models based on site-specific recombinase systems.
- Floxed Mouse: Floxed mouse models provide a way to study gene function in a controlled and tissue-specific manner, allowing researchers to investigate the roles of specific genes in development, physiology, and disease.
- Reporter Mouse: Reporter mouse models generated with SSR technology offer a means to visualize and study gene expression patterns in a tissue-specific or cell-specific manner. They are invaluable tools in deciphering the intricacies of developmental processes and disease mechanisms.
- Inducible Mouse: Inducible mouse models generated with SSR technology are genetically engineered mouse strains that allow for controlled and temporal regulation of gene expression in specific tissues or cell types.
- Recombinase-expressing Mouse: Recombinase-expressing mouse models are genetically modified mouse models that express Cre recombinase tissue-specifically or temporal-specifically.
If you couldn't find the mouse models you need or you are seeking for other model animals, please check out our gene engineering service or just feel free to contact us and get started with our trustable one-stop service.
Our Mouse Models
| STOCK Mirc13tm1Mtm/Mmjax (Cat. No.: CEMM-07250272) | Inquiry | |
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These microRNA cluster 13 (miR-141/miR-200c) conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. LacZ expression is observed in lung and olfactory bulb at late embryonic stages. This mutant mouse strain may be useful in studies of microRNA biology.
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| STOCK Mir130atm1Mtm/Mmjax (Cat. No.: CEMM-07250273) | Inquiry | |
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These microRNA 130a conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. LacZ expression is widepsread. This mutant mouse strain may be useful in studies of microRNA biology.
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| STOCK Mirc27tm1Mtm/Mmjax (Cat. No.: CEMM-07250274) | Inquiry | |
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These microRNA cluster 27 (miR-497/miR-195) conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. LacZ expression is observed in lung at E18.5. This mutant mouse strain may be useful in studies of microRNA biology.
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| STOCK Mirc28tm1Mtm/Mmjax (Cat. No.: CEMM-07250275) | Inquiry | |
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These microRNA cluster 28 (miR-296/miR-298) conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. This mutant mouse strain may be useful in studies of microRNA biology.
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| B6;129-Tg(Drd1-cre)120Mxu/Mmjax (Cat. No.: CEMM-07250551) | Inquiry | |
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Cre recombinase expression is seen in dopamine D1 receptor-expressing neurons.
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| B6.FVB(Cg)-Tg(Mylpf-cre)3Kraj/Mmjax (Cat. No.: CEMM-07250696) | Inquiry | |
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These CRE3 transgenic mice express Cre recombinase under the control of the rat myosin light chain II ventricular (Mylpf or MLC2v) promoter beginning at E11.5 in the brain. This strain may be useful for generating conditional deletions in neurons and their progenitors.
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| FVB/N-Tg(Mylpf-cre)3Kraj/Mmjax (Cat. No.: CEMM-07250554) | Inquiry | |
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These CRE3 transgenic mice express Cre recombinase under the control of the rat myosin light chain II ventricular (Mylpf or MLC2v) promoter beginning at E11.5 in the brain. This strain may be useful for generating conditional deletions in neurons and their progenitors.
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| B6.Cg-Tg(CMV-AR)EMonk/J (Cat. No.: CEMM-07250732) | Inquiry | |
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CMV-stop-AR mice carry a loxP-flanked stop codon upstream of a human androgen receptor gene under the control of a cytomegalovirus promotor. This strain may be useful for generating conditional mutations in studies related to the effects of excess androgen receptor on male typical behaviors.
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| STOCK Tg(CAG-Fgfr3*K650E, -EGFP)10Jheb/J (Cat. No.: CEMM-07250867) | Inquiry | |
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FGFR3-GOF mice conditionally express a mouse Fgfr3 (fibroblast growth factor receptor 3) altered to become constitutively active and an EGFP from the CAG promoter. This mutant mouse strain may be useful in studies related to astrocyte activation and other systems involving fibroblast growth factor signaling.
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| 129S6.Cg-Pex1tm1.1Sjms/Mmjax (Cat. No.: CEMM-07250836) | Inquiry | |
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These Pex1-G844D mice on the 129S6 background exhibit phenotypes consistent with several features of the mild form of Zellweger spectrum disorder (ZSD) including: growth retardation and shortened life expectancy. In addition, this Pex1 allele possesses loxP sites for the creation of conditional knock out animals.
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For Research Use Only.