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C57BL/6J-Slc6a2em1(cre)Lbrl/J
Cat. No.: CEMM-07251128
Common Name: Slc6a2-p2a-Cre
CRISPR-generated Slc6a2-p2a-Cre knock-in mice express cre recombinase from the mouse solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 (Slc6a2) promoter. This strain has been useful in studies of area postrema excitatory neurons as they relate to nausea-associated behaviors.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Slc6a2em1(cre)Lbrl
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| Allele Name |
endonuclease-mediated mutation 1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Slc6a2
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| Gene Name |
solute carrier family 6 (neurotransmitter transporter
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| Chromosome |
8
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6J
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| Molecular Note |
Using the CRISPR/Cas9 technology, a p2a-Cre cassette was inserted into the 3' UTR of the mouse Slc6a2 locus.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J Wild-type from the colony
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| Breeding Considerations |
Heterozygotes and homozygotes are viable and fertile.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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