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B6;129S-Ip6k2tm1Snyd/J
Cat. No.: CEMM-07251058
Common Name: Ip6k2flox
Ip6k2flox mice have loxP sites flanking exon 6 of the inositol hexaphosphate kinase 2 gene. Exposure to Cre recombinase removes the floxed sequence - creating a null allele. These Ip6k2flox mice may be useful in studying cancer and cerebellar development.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Ip6k2tm1Snyd
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Ip6k2
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| Gene Name |
inositol hexaphosphate kinase 2
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| Chromosome |
9
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| MGI Accession ID | show more close |
| Strain of Origin |
129
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| Molecular Note |
A loxP site was inserted upstream of exon 6. An FRT flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 6
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF2/J
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| Breeding Considerations |
Both heterozygous and homozygous mice are viable and fertile with normal breeding, and no reported gross phenotypic or behavioral abnormalities. When maintaining a live colony, heterozygous mice may be bred together, to wildtype mice from the colony or to C57BL/6J inbred mice. Alternatively, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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