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C57BL/6-Tg(Pmch-cre)1Rck/J
Cat. No.: CEMM-07250521
These Tg(Pmch-cre) mice have the pro-melanin-concentrating hormone promoter directing expression of a cre coding sequence in lateral hypothalamus melanin-concentrating hormone neurons.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Pmch-cre)1Rck
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| Allele Name |
transgene insertion 1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Tg(Pmch-cre)1Rck
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| Gene Name |
transgene insertion 1
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| Chromosome |
UN
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Cre-recombinase is expressed in lateral hypothalamus melanin-concentrating hormone neurons.
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| Strain of Origin |
C57BL/6
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| Molecular Note |
Bacterial artificial chromosome (BAC) library (CHORI) was used to identify a BACcontaining the entire mouse pro-melanin-concentrating hormone (Pmch) gene. This BAC was generated to contain a Cre coding sequence downstream from the start codon, and was microinjected into fertilized C57BL/6J oocytes.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, hemizygous mice may be bred to wildtype (non-carrier) mice from the colony or to C57BL/6J inbred mice.
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For Research Use Only.
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