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B6(Cg)-H3c6em1Sjes/J
Cat. No.: CEMM-07251099
Common Name: H3.1-iCOUNT
H3.1-iCOUNT (inducible cell division counter) knock-in mice carry a loxP-flanked mCherry reporter followed by an EGFP reporter inserted upstream of the H3c6 (H3 clustered histone 6, also called H3.1) stop codon. Mice may be used to label cell division events in vivo.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
H3c6em1Sjes
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| Allele Name |
endonuclease-mediated mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); Reporter
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| Gene Symbol |
H3c6
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| Gene Name |
H3 clustered histone 6
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| Chromosome |
13
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6
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| Molecular Note |
CRISPR-targeting inserted a recombination-induced tag exchange (RITE) containing a loxP site, mCherry reporter gene, T2A, neomycin resistance cassette, loxP site, and EGFP reporter gene.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, heterozygous mice may be bred together, to wildtype (non-carrier) mice from the colony or to C57BL/6J inbred mice. Alternatively, the donating investigator reports that homozygous mice are viable, fertile, and may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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