Online Inquiry
C57BL/6-Agpat5tm1Thor/J
Cat. No.: CEMM-07251127
Common Name: Agpat5flox
Exon 3 of the mouse Agpat5 (1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon) gene is flanked by lox2272/loxP sites in these Agpat5flox mice. Cre recombinase-mediated excision of the floxed region results in a knock-out allele and expression of a tdTomato reporter useful in studies of agouti-related peptide neurons and their roles in insulin-induced hypoglycemia sensing and glucagon secretion.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Agpat5tm1Thor
show more
close
|
| Allele Name |
targeted mutation 1
show more
close
|
| Allele Attributes |
Conditional ready (e.g. floxed); Reporter
show more
close
|
| Gene Symbol |
Agpat5
show more
close
|
| Gene Name |
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase
show more
close
|
| Chromosome |
8
show more
close
|
| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6N
show more
close
|
| Molecular Note |
A lox2272 site was inserted upstream of exon 3 and a loxP site, tdTomato gene in opposite orientation, second lox2272, neomycin resistance gene, and second loxP site were inserted downstream of exon 3.
show more
close
|
| HUSBANDRY | |
|---|---|
| Breeding Considerations |
Floxed heterozygotes and homozygotes are viable and fertile.
show more
close
|
| Breeding Strategy |
Heterozygote x Heterozygote
show more
close
|
For Research Use Only.
Related Products