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C57BL/6J-Tg(Nrl-cre)1Smgc/J
Cat. No.: CEMM-07250707
Common Name: Nrl-Cre
These Nrl-Cre mice recapitulate developmental expression patterns of the endogenous mouse Nrl gene without any overt impact on retinal structure or function. They enable rod precursor cell-specific excision of floxed genomic segments in retinal models of neurogenesis and differentiation.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Nrl-cre)1Smgc
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| Allele Name |
transgene insertion 1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Tg(Nrl-cre)1Smgc
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| Gene Name |
transgene insertion 1
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| Chromosome |
UN
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Rod precursors of the eye.
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| Strain of Origin |
C57BL/6J
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| Molecular Note |
The transgenic vector includes a 1.7 kb mouse Nrl promoter and Nrl exons 1 and 2 driving Cre recombinase expression. Cre is expressed specifically in the rod precursors of the eye.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J Noncarrier
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| Breeding Considerations |
Hemizygotes are viable and fertile. Homozygous viability/fertility have not been determined.
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For Research Use Only.
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