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B6N.129(Cg)-Kdm1atm2.1Rsd/J
Cat. No.: CEMM-07250896
Common Name: Lsd1n flox
Exon 8a of the mouse Kdm1a (LSD1) gene is flanked by loxP sites in this conditional mutant strain. Cre-mediated excision of the exon results in a knock-out of the Lsd1n neuron-specific isoforms of the gene involved with neurite morphogenesis, learning, and memory.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Kdm1atm2.1Rsd
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| Allele Name |
targeted mutation 2.1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Kdm1a
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| Gene Name |
lysine (K)-specific demethylase 1A
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| Chromosome |
4
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
Exon 8a was floxed. Flp-mediated recombination removed the neomycin resistance cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6NJ
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| Breeding Considerations |
Heterozygotes and homozygotes are viable and fertile.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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