Online Inquiry
STOCK Adgrl1tm2c(EUCOMM)Hmgu/SudJ
Cat. No.: CEMM-07251011
Common Name: Lphn1 cKO
Exon 4 of the mouse Adgrl1 gene is flanked by loxP sites in this Lphn1 cKO strain. Cre recombinase-mediated excision of exon 4 generates and out-of-frame mutation. Loss of ADGRL1/LPHN1 protein has not been validated due to a lack of reliable antibody, but neurons from homozygous excised mice exhibit massive synaptic phenotypes.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Adgrl1tm2c(EUCOMM)Hmgu
show more
close
|
| Allele Name |
targeted mutation 2c
show more
close
|
| Allele Attributes |
Conditional ready (e.g. floxed)
show more
close
|
| Gene Symbol |
Adgrl1
show more
close
|
| Gene Name |
adhesion G protein-coupled receptor L1
show more
close
|
| Chromosome |
8
show more
close
|
| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6N-Atm1Brd
show more
close
|
| Molecular Note |
The following were introduced to intron 3: FRT En2 SA-IRES-lacZ-pA-loxP-hbactP-Neo-pA-FRT loxP, and a loxP site was placed in intron 4. Flp-mediated recombination removed the FRT flanked lacZ and neo cassettes.
show more
close
|
For Research Use Only.
Related Products