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B6.FVB-Tg(Otp-cre)1Hzo/J
Cat. No.: CEMM-07250815
Common Name: Otp-Cre
These Otp-cre mice express Cre recombinase in hypothalamic and medial amygdala neurons.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Otp-cre)1Hzo
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| Allele Name |
transgene insertion 1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Tg(Otp-cre)1Hzo
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| Gene Name |
transgene insertion 1
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| Chromosome |
UN
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
When crossed with strains carrying loxP-flanked sequences of interest, floxed regions are excised in Otp-lineage cells in the hypothalamus and medial amygdala.
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| Strain of Origin |
FVB/N
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| Molecular Note |
BAC RP24-337G4 containing the Otp locus was modified by recombineering to replace the Otp coding sequence with a Cre-recombinase. This BAC also incorporates exons 2-4 of the Tbca gene; no other genes are incorporated. This modified BAC was microinjected into fertilized oocytes.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J C57BL/6NJ
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| Breeding Considerations |
Hemizygotes are viable and fertile. Homozygous viability/fertility have not been tested.
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| Breeding Strategy |
Noncarrier x Hemizygote
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For Research Use Only.
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