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B6.Cg-Tg(Thy1-cre/ERT2, -EYFP)AGfng/J

Cat. No.: CEMM-07250066

Common Name: SLICK line A; SLICK-A
These transgenic mice ("SLICK" for single-neuron labeling with inducible Cre-mediated knock-out) have a tamoxifen inducible Cre-mediated recombination system and Enhanced Yellow Fluorescent Protein driven by 2 bidirectional copies of the mouse thymus cell antigen 1 promoter. When crossed with a strain containing a loxP site flanked sequence of interest. The Donating Investigator reports that founder line A mice express the transgene in small subsets of motor neurons and dorsal root ganglion neurons.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Tg(Thy1-cre/ERT2,-EYFP)AGfng
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Allele Name
transgene insertion A
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Allele Attributes
Recombinase-expressing; Reporter; Inducible
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Gene Symbol
Tg(Thy1-cre/ERT2,-EYFP)AGfng
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Gene Name
transgene insertion A
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Chromosome
UN
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Expressed Genes
YFP, Yellow Fluorescent Protein, jellyfish; cre/ERT2, Cre recombinase and estrogen receptor 1 (human) fusion gene
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MGI Accession ID
3719910
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Site of Expression
Tamoxifen-inducible Cre and YFP in subsets of motor neurons and dorsal root ganglion neurons, and in many neurons of the cortex, hippocampus (both CA1 and dentate granule cells) and cerebellar mossy fibers
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Strain of Origin
(C57BL/6 x SJL)F1
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Molecular Note
Transgenic mice have a tamoxifen-inducible Cre-mediated recombination system and Enhanced Yellow Fluorescent Protein driven by 2 bidirectional copies of the mouse thymus cell antigen 1 promoter.
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HUSBANDRY
Suggested Controls
C57BL/6J
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Breeding Considerations
When maintaining a live colony, these mice may be bred as homozygotes.
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For Research Use Only.
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