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B6(Cg)-Rhoqtm1.1Pkm/J
Cat. No.: CEMM-07250835
Common Name: Rhoq flox (TC10 flox)
These floxed mutant mice possess loxP sites flanking exon 2 of the Rhoq gene. This strain may be useful for generating conditional mutations in applications related to actin cytoskeleton reorganization, the immune synapse, and the insulin pathway.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Rhoqtm1.1Pkm
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Rhoq
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| Gene Name |
ras homolog family member Q
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| Chromosome |
17
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6J
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| Molecular Note |
The selection cassette contains an FRT flanked neomycin cassette, followed by a 3' loxP site inserted downstream of exon 2, and another loxP site inserted upstream of exon 2. Flp-mediated recombination removed the FRT flanked neo cassette leaving exon 2 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J Wild-type from the colony
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| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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