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C57BL/6-Nrxn1tm5Sud/J
Cat. No.: CEMM-07250605
Nrxn1flox mice may be useful for generating tissue specific deletions of neurexin I in neuronal cells.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Nrxn1tm5Sud
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| Allele Name |
targeted mutation 5
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Nrxn1
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| Gene Name |
neurexin I
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| Chromosome |
17
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6
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| Molecular Note |
A targeting vector was designed to insert a loxP site upstream of exon 21, and a FRT flanked neomycin resistance (neo) cassette, followed by a second loxP site, downstream of exon 21. Also, splice site 4, upstream of exon 21, was mutated to a canonical splice acceptor sequence.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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