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B6.Cg-Npy1rtm1.1(cre/GFP)Rpa/J
Cat. No.: CEMM-07250811
Common Name: Npy1rcre:GFP
These targeted mutant mice express cre recombinase from the mouse Npyr1 (neuropeptide Y receptor Y1) promoter and have been useful in tracing synaptic networks.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Npy1rtm1.1(cre/GFP)Rpa
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Recombinase-expressing; Reporter
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| Gene Symbol |
Npy1r
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| Gene Name |
neuropeptide Y receptor Y1
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| Chromosome |
8
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
When crossed with mice expressing a floxed stop reporter Cre expression is detected in the anterior-dorsal, anterior ventral, posterior dorsal and posterior ventral medial amygdala. Although GFP fluorescence is incorporated in the targeting construct, it is too low to be visualized directly or through immunohistochemistry.
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| Strain of Origin |
(129S6/SvEvTac x C57BL/6NCrl)F1
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| Molecular Note |
A Cre/GFP fusion gene with a neo cassette was inserted just 5' fo the normal initiation codon for Npy1r gene. The neo cassette was then removed by action of FLP recombinase.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J Wild-type from the colony
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| Breeding Considerations |
Heterozygotes and homozygotes are viable and fertile.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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