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B6.129S7-Itga3tm1Rdav/J
Cat. No.: CEMM-07250132
These f(α3) mutant mice harbor loxP sites flanking exons 11-18 of the Itga3 (integrin alpha 3 (or alpha3-integrin (α3-integrin)) gene and may be useful in generating conditional mutations for studying the role of Itga3 transmembrane cell adhesion receptors in neuronal functions in the developing and adult central nervous system, including synaptic plasticity and memory formation.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Itga3tm1Rdav
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Itga3
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| Gene Name |
integrin alpha 3
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| Chromosome |
11
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| MGI Accession ID | show more close |
| Strain of Origin |
129S7/SvEvBrd-Hprtb-m2
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| Molecular Note |
A loxP site was inserted upstream of exon 11 and a floxed neo cassette was inserted downstream of exon 18. Transient Cre expression in ES cells removed the floxed neo cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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