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B6.Cg-Ckap5tm1.1Eba/J
Cat. No.: CEMM-07250922
Common Name: TOG flox
Floxed TOG mice possess loxP sites flanking exons 4-6 of the cytoskeleton associated protein 5 (Ckap5) gene. These floxed mice are useful when studying the role of TOG in microtubule dynamics regulation and myelination.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Ckap5tm1.1Eba
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Ckap5
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| Gene Name |
cytoskeleton associated protein 5
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| Chromosome |
2
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| MGI Accession ID | show more close |
| Strain of Origin |
(129S6/SvEvTac x C57BL/6J)F1
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| Molecular Note |
The targeting construct consists of a loxP sequence inserted into intron 3 and a FRT PGKNeo-FRT loxP cassette inserted in intron 6 of the BAC clone RP23-118G11. The FRT flanked Neo was removed via FLP-mediated recombination.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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