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B6.Cg-Ccn3tm1.1Jt/J
Cat. No.: CEMM-07250685
Common Name: Novflx
Exons 3 and 4 of the mouse Nov gene are flanked by loxP sites. Brain-specific cre-mediated excision of the floxed region in the brain results in a mild anxiolytic effect.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Ccn3tm1.1Jt
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Ccn3
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| Gene Name |
cellular communication network factor 3
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| Chromosome |
15
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| MGI Accession ID | show more close |
| Strain of Origin |
B6(Cg)-Tyrc-2J/J
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| Molecular Note |
BAC clone RP24-289J3, containing the mouse Nov gene, was used to introduce an FRT flanked neomycin resistance gene followed by a loxP site in intron 2, and another loxP site in intron 4. Flp-mediated recombination removed the FRT flanked neo cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
Homozygous and heterozygous floxed mice are viable and fertile.
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For Research Use Only.
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