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B6.Cg-Brs3tm1.1(cre/GFP)Rpa/J
Cat. No.: CEMM-07250808
Common Name: Brs3-iresCRE:GFP
IRES-cre is expressed from the mouse Brs3 promoter in Brs3-expressing cells of the parabrachial nucleus (PBN).
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Brs3tm1.1(cre/GFP)Rpa
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Recombinase-expressing; Reporter
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| Gene Symbol |
Brs3
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| Gene Name |
bombesin-like receptor 3
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| Chromosome |
X
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
IRES-Cre is expressed from the mouse Brs3 promoter in Brs3-expressing cells of the parabrachial nucleus.
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| Strain of Origin |
(129S6/SvEvTac x C57BL/6NCrl)F1
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| Molecular Note |
IRES-Myc tag-nuclear localization signal (NLS)-Cre-GFP-FRT neomycin-FRT were introduced just after the termination codon of the X-linked mouse Brs3 gene via homologous recombination. The neomycin cassette was excised through crosses with animals broadly expressing Flp recombinase.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J Wild-type from the colony
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| Breeding Considerations |
This mutation is X-linked. Heterozygotes/hemizygotes are viable and fertile. Although untested, homozygotes are anticipated to be viable and fertile.
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| Breeding Strategy |
Homozygote x Hemizygote
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For Research Use Only.
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