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B6.Cg-Atoh1em1(cre)Zyliu/J
Cat. No.: CEMM-07251094
Common Name: Atoh13*HA-P2A-Cre
Atoh13*HA-P2A-Cre knock-in mice carry a CRISPR/Cas9 generated insertion of three HA tags and Cre recombinase just upstream of the stop codon of the Atoh1 gene. These mice are useful for lineage tracing, cell sorting, and gene manipulation of multiple cell types including cochlear hair cells (HCs).
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Atoh1em1(cre)Zyliu
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| Allele Name |
endonuclease-mediated mutation 1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Atoh1
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| Gene Name |
atonal bHLH transcription factor 1
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| Chromosome |
6
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6 x DBA/2
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| Molecular Note |
Using CRISPR/Cas9 technology, three hemagglutinin (HA) tags, a P2A ribosomal skip cleavage peptide sequence, and a Cre recombinase were inserted immediately before the stop codon of the atonal bHLH transcription factor 1 (Atoh1) gene.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6NJ
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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