Online Inquiry
B6;CBA-Tg(Fgfr3-icre/ERT2)4-2Wdr/J
Cat. No.: CEMM-07250578
Fgfr3-icreERT2 mice express codon optimized iCreERT2 in forebrain subventricular zone progenitor cells and astrocytes making them useful for applications requiring tamoxifen-induced deletion of floxed sequences in these cells.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Fgfr3-icre/ERT2)4-2Wdr
show more
close
|
| Allele Name |
transgene insertion 4-2
show more
close
|
| Allele Attributes |
Recombinase-expressing; Inducible
show more
close
|
| Gene Symbol |
Tg(Fgfr3-icre/ERT2)4-2Wdr
show more
close
|
| Gene Name |
transgene insertion 4-2
show more
close
|
| Chromosome |
UN
show more
close
|
| Expressed Genes |
cre/ERT2, Cre recombinase and estrogen receptor 1 (human) fusion gene
show more
close
|
| MGI Accession ID | show more close |
| Site of Expression |
Mice carrying this transgene express Cre-ERT2 protein in forebrain subventricular zone progenitor cells and astrocytes.
show more
close
|
| Strain of Origin |
(C57BL/6 x CBA)F1
show more
close
|
| Molecular Note |
A mouse PAC clone (RPCI21-608P12) containing the Fgfr3 gene was modified by the insertion of iCreERT2 and an SV40polyA sequence into exon 2 (the first coding exon).
show more
close
|
| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6CBAF1/J
show more
close
|
| Breeding Considerations |
When maintaining a live colony hemizygous mice may be bred to wildtype (non-carrier) mice from the colony or to C57BL/6J.
show more
close
|
For Research Use Only.
Related Products