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STOCK Tenm3em2.1Luo/J
Cat. No.: CEMM-07250887
Common Name: Ten3fl; Ten3flox
Exon 4 of the mouse Tenm3 gene is flanked by loxP sites in this Ten3flox conditional mutant strain. Cre-mediated excision of the floxed region results in a knock-out allele.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tenm3em2.1Luo
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| Allele Name |
endonuclease-mediated mutation 2.1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Tenm3
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| Gene Name |
teneurin transmembrane protein 3
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| Chromosome |
8
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| MGI Accession ID | show more close |
| Strain of Origin |
(C57BL/6 x 129S6/SvEvTac)F1
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| Molecular Note |
CRISPR/Cas9 endonuclease mediated genome editing is used to introduce a reversed loxP site to intron 3 and an FRT flanked PGK-neomycin resistance cassette and reversed loxP site is placed in intron 4. Flp-mediated recombination removed the FRT flanked neo cassette leaving exon 4 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
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| Breeding Considerations |
Homozygotes and heterozygotes are viable and fertile.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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