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B6;129-Pitx2tm1.1Sac/J
Cat. No.: CEMM-07250389
Common Name: Pitx2flox
These Pitx2flox mice are useful when studying heart, eye, and pituitary gland development.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Pitx2tm1.1Sac
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Pitx2
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| Gene Name |
paired-like homeodomain transcription factor 2
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| Chromosome |
3
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
Gene targeting was performed with a vector engineered to contain a loxP site downstream from exon 4 and a floxed neomycin cassette upstream of exon 4. The floxed neo cassette was excised by transient Cre expression leaving exon 4 flanked by loxP sites.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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