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C57BL/6-Per2tm3Jt/J
Cat. No.: CEMM-07251024
Common Name: Color-Switch PER2::LUC
Color-Switch PER2::LUC reporter mice switch from click beetle red PER2 (period circadian clock 2)::LUCIFERASE protein expression to click beetle green PER2::LUCIFERASE expression upon cre recombination. This enables cell-type-specific circadian measurements.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Per2tm3Jt
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| Allele Name |
targeted mutation 3
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| Allele Attributes |
Conditional ready (e.g. floxed); Reporter
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| Gene Symbol |
Per2
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| Gene Name |
period circadian clock 2
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| Chromosome |
1
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6N
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| Molecular Note |
A loxP-CBR (click beetle red luciferase) cDNA-neomycin (reversed)-Stop-loxP-CBG99 (click beetle green luciferase) cDNA cassette was introduced to the 3' end of the full length mouse Per2 open reading frame (ORF) in exon 23. The ATG start codons were omitted from the CBR and CBG components to minimize non-specific expression.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6NJ
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| Breeding Considerations |
Heterozygotes and homozygotes are viable and fertile.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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