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B6.129S4-Xisttm2Jae/GribJ
Cat. No.: CEMM-07251116
Common Name: Xist2lox
Xist2lox/2lox floxed mice have loxP sites flanking exons 1-3, as well as 5 kb of the proximal promoter, of the X-linked Xist gene. These mice may be useful when studying X chromosome inactivation and reactivation.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Xisttm2Jae
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| Allele Name |
targeted mutation 2
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Xist
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| Gene Name |
inactive X specific transcripts
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| Chromosome |
X
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| MGI Accession ID | show more close |
| Strain of Origin |
129S4/SvJae
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| Molecular Note |
Exons 1, 2, and 3 as well as 5 kb of the proximal promoter were left floxed after the sequential insertion of single loxP sites.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous and hemizygous mice may be bred together. Please note that Xist is on the X chromsome..
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| Breeding Strategy |
Homozygote x Hemizygote; Heterozygote x Hemizygote
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For Research Use Only.
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