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B6;129S4-Ror1tm1.1Meg/J
Cat. No.: CEMM-07250396
These Ror1f/f conditional mutant mice may have applications in studies related to Wnt5a-mediated signaling during embryonic development.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Ror1tm1.1Meg
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Ror1
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| Gene Name |
receptor tyrosine kinase-like orphan receptor 1
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| Chromosome |
4
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| MGI Accession ID | show more close |
| Strain of Origin |
129S4/SvJae
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| Molecular Note |
A loxP site was inserted upstream of exon 3 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 4 via homologous recombination. Flp mediated recombination removed the neo cassette. Western blot analysis confirms protein expression in homozygous mice is similar to wild-type levels.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF1/J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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