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B6;129S-Serpina3ntm1.1Lbrl/J
Cat. No.: CEMM-07250637
Common Name: Serpina3nfl
Serpina3nfl/fl floxed mice may be useful for developing therapeutic approaches to relieve receptor-activated neuropathic pain.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Serpina3ntm1.1Lbrl
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Serpina3n
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| Gene Name |
serine (or cysteine) peptidase inhibitor
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| Chromosome |
12
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| MGI Accession ID | show more close |
| Strain of Origin |
129S6/SvEvTac
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| Molecular Note |
A targeting vector was designed to insert a loxP site upstream of exon 2, and a FRT flanked neomycin resistance (neo) cassette followed by a second loxP site downstream of exon 2. Flp-mediated recombination removed the selection cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF2/J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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