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B6;129S-Hoxb1tm1(cre)Og/J
Cat. No.: CEMM-07250221
These Hoxb1 Cre recombinase knock-in mice may be useful for generating mutations to study fate mapping of cell lineages derived from rhombomere 4 (r4) of the hindbrain.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Hoxb1tm1(cre)Og
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Hoxb1
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| Gene Name |
homeobox B1
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| Chromosome |
11
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Cre mediated recombination is detected in almost all tissues caudal to the hindbrain at age embryonic day 10.5 (spinal cord, peripheral nervous system, axial and appendicular musculature, and mesenchymal tissues).
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| Strain of Origin |
129S/SvEv-Gpi1c
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| Molecular Note |
The open reading frame was replaced with an in-frame Cre open reading frame.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
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| Breeding Considerations |
When maintaining a live colony, these mice can be bred as female heterozygotes and male homozygotes. The Donating Investigator reports that although female homozygotes are viable and fertile they are poor mothers.
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For Research Use Only.
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