B6;129S4-Cdh8tm2c(KOMP)Wtsi/DlbeJ

Cat. No.: CEMM-07251119

Common Name: Cdh8FL
Cdh8FL/FL mice have loxP sites flanking exon 3 of the cadherin 8 gene, making them useful for studying synaptic adhesion, axon outgrowth and guidance.
Inquiry
Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Cdh8tm2c(KOMP)Wtsi
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Allele Name
targeted mutation 2c
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Allele Attributes
Conditional ready (e.g. floxed)
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Gene Symbol
Cdh8
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Gene Name
cadherin 8
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Chromosome
8
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MGI Accession ID show more close
Strain of Origin
C57BL/6N-Atm1Brd
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Molecular Note
The cassette is composed of an FRT site, a beta galactosidase sequence, a loxP site, a neomycin resistance (neo) cassette, second FRT site and a second loxP site and is inserted upstream of exon 3. A third loxP site is inserted downstream of exon 3. Flp-mediated recombination removed the lacZ and neo cassette.
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HUSBANDRY
Suggested Controls
C57BL/6J
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Breeding Considerations
When maintaining a live colony, homozygous mice may be bred together.
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Breeding Strategy
Heterozygote x Heterozygote
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For Research Use Only.
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