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B6;129-Gt(ROSA)26Sortm4(CAG-EGFP*)Nat/J
Cat. No.: CEMM-07250448
In this conditional Gt(ROSA)26Sor (gene trap ROSA 26, Philippe Soriano) knock-in strain, Cre excision of a floxed stop cassette enables expression of GFP that is specifically localized to mitochondria. A C-terminal V5 epitope tag is also fused to GFP.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Gt(ROSA)26Sortm4(CAG-EGFP*)Nat
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| Allele Name |
targeted mutation 4
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| Allele Attributes |
Conditional ready (e.g. floxed); Reporter
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| Gene Symbol |
Gt(ROSA)26Sor
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| Gene Name |
gene trap ROSA 26
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| Chromosome |
6
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| Expressed Genes |
GFP, Green Fluorescent Protein
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| MGI Accession ID | show more close |
| Site of Expression |
Cre excision of a floxed stop cassette enables expression of GFP that is specifically localized to mitochondria.
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| Strain of Origin |
129
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| Molecular Note |
A targeting vector containing (from 5' to 3') a CAG promoter, a loxP-flanked transcription STOP cassette, the N-terminal 25 amino acid mitochondrial-targeting sequence of cytochrome c oxidase VIIIa (C8a), EGFP fused to a C-terminal triple V5 epitope, a bovine growth hormone 3' UTR, and a Frt-PGKneo-Frt cassette was inserted into the locus.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
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| Breeding Considerations |
Homozygotes and heterozygotes are viable and fertile.
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| Breeding Strategy |
Hemizygote x Hemizygote
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For Research Use Only.
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