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B6;129S-Grptm2Zfc/J
Cat. No.: CEMM-07250942
Common Name: GrpF
GrpF mice possess loxP sites flanking exon 1 of the gastrin releasing peptide (Grp) gene. These floxed mice are useful when studying non-histaminergic scratching behavior.This contains a frt-flanked neo cassette within the floxed region. It is unknown if this affects expression of the endogenous protein. As such, this strain was bred to a Flpo recombinase expressing mouse line, to remove the neo cassette. This new strain, lacking neo, is available as.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Grptm2Zfc
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| Allele Name |
targeted mutation 2
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Grp
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| Gene Name |
gastrin releasing peptide
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| Chromosome |
18
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| MGI Accession ID | show more close |
| Strain of Origin |
129S7/SvEvBrd-Hprt+
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| Molecular Note |
The targeting vector is designed to insert a loxP site upstream of exon 1, and an FRT flanked neomycin selection cassette followed by a second loxP site downstream of exon 1 of the gene.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF2/J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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