STOCK Tdgf1tm2.2Mms/J

Cat. No.: CEMM-07250309

These Cripto2loxP mice possess a loxP-sites flanking exons 3-5 of the teratocarcinoma-derived growth factor 1 (Tdgf1) gene. This strain may be useful for studying embryonic development and tumor growth.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Tdgf1tm2.2Mms
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Allele Name
targeted mutation 2.2
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Allele Attributes
Conditional ready (e.g. floxed); No functional change
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Gene Symbol
Tdgf1
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Gene Name
teratocarcinoma-derived growth factor 1
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Chromosome
9
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MGI Accession ID show more close
Strain of Origin
129S6/SvEvTac
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Molecular Note
A targeting vector was designed to insert a loxP-flanked neomycin resistance (neo) cassette downstream of exon 5, and a single loxP site downstream of exon 2 of the teratocarcinoma-derived growth factor 1 (Tdgf1) gene. Cre-mediated recombination removed the neo cassette and left exons 3 through 5 floxed.
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HUSBANDRY
Suggested Controls
C57BL/6NJ
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Breeding Considerations
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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