Online Inquiry
B6;129-Pax3tm1(cre)Joe/J
Cat. No.: CEMM-07250026
Common Name: Pax3Cre KI
Cre recombinase expression is detected in the dorsal neural tube and somites of early embryos and in neural crest and somite derivatives of later gestation embryos. This knock-in mutant mouse strain represents a model that may be useful in studies of development and lineage mapping of neural crest and somite derivatives
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Pax3tm1(cre)Joe
show more
close
|
| Allele Name |
targeted mutation 1
show more
close
|
| Allele Attributes |
Recombinase-expressing
show more
close
|
| Gene Symbol |
Pax3
show more
close
|
| Gene Name |
paired box 3
show more
close
|
| Chromosome |
1
show more
close
|
| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
show more
close
|
| MGI Accession ID | show more close |
| Site of Expression |
Dorsal neural tube and somites of embryonic day 9-11.5 embryos and in the cardiac neural crest cells and colonic epithelia of embryonic day 11.5 embryos
show more
close
|
| Strain of Origin |
Not Specified
show more
close
|
| Molecular Note |
A targeting vector was desinged to insert the Cre recombinase cDNA followed by a stop codon and a polyA signal in place of exon 1 of the endogenous locus.
show more
close
|
| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF1/J
show more
close
|
| Breeding Considerations |
When maintaining a live colony, these mice are bred as heterozygotes. Homozygous mice have an embryonic lethal phenotype, failing to develop past embryonic day 18.5.
show more
close
|
For Research Use Only.
Related Products