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STOCK Mir301tm1Mtm/Mmjax
Cat. No.: CEMM-07250259
These microRNA 301 conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. LacZ expression is widespread. This mutant mouse strain may be useful in studies of microRNA biology.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Mir301tm1Mtm
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); Reporter; Null/Knockout
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| Gene Symbol |
Mir301
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| Gene Name |
microRNA 301
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| Chromosome |
11
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| Expressed Genes |
lacZ, beta-galactosidase, E. coli
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| MGI Accession ID | show more close |
| Site of Expression |
Ubiquitous at E11.5
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| Strain of Origin |
129P2/OlaHsd
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| Molecular Note |
A targeting vector was designed to insert an FRT site followed by a lacZ gene, a loxP site, a neomycin cassette, an FRT site and a loxP site (FRT lacZ-loxP-Neo-FRT loxP) upstream of the microRNA stem loop and one loxP site immediately downstream of the microRNA stem loop.
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| HUSBANDRY | |
|---|---|
| Breeding Considerations |
While maintaining a live colony, these mice are bred as heterozygotes. Mice homozygous for the mutation are not viable.
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For Research Use Only.
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