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STOCK Lmx1btm4.1Rjo/J
Cat. No.: CEMM-07250852
Common Name: Lmx1blox
Lmx1blox/lox mice possess loxP sites flanking exons 4-6 of the LIM homeobox transcription factor 1 beta gene. These floxed mice are useful for tissue-specific deletion of Lmx1b when studying the role of this gene in nail-patella syndrome.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Lmx1btm4.1Rjo
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| Allele Name |
targeted mutation 4.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Lmx1b
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| Gene Name |
LIM homeobox transcription factor 1 beta
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| Chromosome |
2
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| MGI Accession ID | show more close |
| Strain of Origin |
129S7/SvEvBrd-Hprt+
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| Molecular Note |
LoxP sites were inserted into introns 4 and 6, flanking sequence that encodes the homeodomain. The construct also contains a loxP-flanked neomycin selection cassette. A Cre expression plasmid was used to remove the floxed neo cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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