B6;129-Nrxn3tm3Sud/J

Cat. No.: CEMM-07250288

Common Name: N3F
Exon 18 of these Nrxn3 (neurexin III) targeted mutant mice is flanked by loxP sites. This strain may be useful in generating tissue-specific alpha and beta isoform knock-outs for use in a variety of neurobiological studies.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Nrxn3tm3Sud
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Allele Name
targeted mutation 3
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Allele Attributes
Conditional ready (e.g. floxed); No functional change
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Gene Symbol
Nrxn3
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Gene Name
neurexin III
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Chromosome
12
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MGI Accession ID show more close
Strain of Origin
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Molecular Note
Exon 18 (the first common coding exon for the alpha and beta transcripts) was flanked by loxP sites and an FRT flanked neomycin selection cassette was placed in the 5' intron. Flp-mediated recombination removed the neo cassette.
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HUSBANDRY
Suggested Controls
C57BL/6J
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Breeding Considerations
When maintained as a live colony, homozygotes or heterozygotes may be bred.
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For Research Use Only.
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