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STOCK Flnatm1.1Caw/J
Cat. No.: CEMM-07250205
These mice harbor a conditional knockout allele of the Flna gene. When bred to mice expressing cre recombinase, the floxed exons are deleted in the tissues expressing cre in the offspring. This strain may be useful in mechanistic studies of neuronal and cardiovascular development.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Flnatm1.1Caw
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Flna
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| Gene Name |
filamin
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| Chromosome |
X
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| MGI Accession ID | show more close |
| Strain of Origin |
129S4/SvJae
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| Molecular Note |
A combination of homologous recombination and transient Cre expression resulted in the flanking of exons 3-7 with loxP sites.
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| HUSBANDRY | |
|---|---|
| Breeding Considerations |
When maintained as a live colony homozygous/hemizyous animals may be bred. The targeted gene is X-linked.
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For Research Use Only.
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