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Mouse Models
Site-specific recombinase (SSR) system is widely used in genetically modification, especially the generation for conditional KO and inducible KO mouse models. For making it more efficient and easier, mouse models with special functions have been generated, such as tissue-specifically expressing Cre, inducible expressing Cre, Split-Cre, floxed (target gene were flanked by loxP sites) mouse, et al.
For assisting our global customers making better breakthrough in their research areas, Creative Biogene offers various of mouse models based on site-specific recombinase systems.
- Floxed Mouse: Floxed mouse models provide a way to study gene function in a controlled and tissue-specific manner, allowing researchers to investigate the roles of specific genes in development, physiology, and disease.
- Reporter Mouse: Reporter mouse models generated with SSR technology offer a means to visualize and study gene expression patterns in a tissue-specific or cell-specific manner. They are invaluable tools in deciphering the intricacies of developmental processes and disease mechanisms.
- Inducible Mouse: Inducible mouse models generated with SSR technology are genetically engineered mouse strains that allow for controlled and temporal regulation of gene expression in specific tissues or cell types.
- Recombinase-expressing Mouse: Recombinase-expressing mouse models are genetically modified mouse models that express Cre recombinase tissue-specifically or temporal-specifically.
If you couldn't find the mouse models you need or you are seeking for other model animals, please check out our gene engineering service or just feel free to contact us and get started with our trustable one-stop service.
Our Mouse Models
| B6.129-Kdm1atm1.1Sho/J (Cat. No.: CEMM-07250520) | Inquiry | |
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These LSD1fl/fl mutant mice may be useful for studying the epigenetic mechanisms required for proper hematopoietic maturation, as well as the role of LSD1 in activity-evoked transcription of immediate early genes (IEGs) that impact memory formation, emotional behavior and information processing.
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| B6.Cg-Gt(ROSA)26Sortm32(CAG-COP4*H134R/EYFP)Hze/J (Cat. No.: CEMM-07250531) | Inquiry | |
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Ai32 mice express an improved channelrhodopsin-2/EYFP fusion protein following exposure to Cre recombinase. These mice can be used in optogenetic studies for rapid in vivo activation of excitable cells by illumination with blue light (450-490 nm).
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| B6.129S1(SJL)-Nkx2-5tm2(cre)Rph/J (Cat. No.: CEMM-07250544) | Inquiry | |
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The Nkx2-5IRESCre allele expresses an IRES-Cre fusion protein in cardiac crescent and heart tube progenitor cells.
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| C57BL/6-Cxcr2tm1Rmra/J (Cat. No.: CEMM-07250545) | Inquiry | |
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Cxcr2fl/fl floxed mice may be useful for studying the neutrophil granulocyte lineage and the migration of neutrophils during infection.
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| B6.129S1-Tgm2tm1Rmgr/J (Cat. No.: CEMM-07250546) | Inquiry | |
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These Tgm2t/t floxed mice may be useful for studying the regulation of cell adhesion and protein aggregation.
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| B6.129(Cg)-Fa2htm1.2Hama/J (Cat. No.: CEMM-07250552) | Inquiry | |
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These Fa2hflox/flox mice may be useful for studying the lipid profile of myelin disorders of the central nervous system.
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| B6;SJL-Nlgn2tm1.1Sud/J (Cat. No.: CEMM-07250566) | Inquiry | |
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FN2 mice have exons 3-5 of the neuroligin 2 (Nlgn2) gene floxed, and may be useful for studying synapse formation and/or function.
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| STOCK Mef2ctm1Jjs/J (Cat. No.: CEMM-07250567) | Inquiry | |
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Mef2cflox/flox may be useful for studying the temporal- and tissue-specific distribution of MEF2C.
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| STOCK Ptpn11tm1.1Wbm/J (Cat. No.: CEMM-07250575) | Inquiry | |
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Shp2fl floxed mice may be useful for studying Schwann cell regulation of axon outgrowth and myelination.
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| B6;129-Tor1atm3.1Wtd/J (Cat. No.: CEMM-07250579) | Inquiry | |
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Tor1aflox/flox mice possess loxP sites flanking exons 3-5 of the Tor1a gene, making this stain useful for studying DYT1 dystonia.
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